Published this week in Nature Machine Intelligence.
TiD News: August 2021
New Publication, “A machine learning platform to estimate, anti-SARS-CoV-2 activities” by Tudor Oprea, MD, PhD and Team:
Govinda B. KC, Giovanni Bocci, Srijan Verma, Md Mahmudulla Hassan, Jayme_Holmes, Jeremy J. Yang & Suman Sirimulla.
New Publication by Christophe Lambert and Team. Congratulations!
“Using Machine Learning Imputed Outcomes to Assess Drug-Dependent Risk of Self-Harm in Patients with Bipolar Disorder: A Comparative Effectiveness Study“. https://doi.org/10.2196/24522
Christophe Lambert: Linkedin Article
This third edition volume expands on the previous editions with new topics that cover drug discovery through translational bioinformatics, informatics, clinical research informatics, as well as clinical informatics. The chapters discuss new methods to study target identification, genome analysis, cheminformatics,
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Virtual screening is a well-established technique that has proven to be successful in the identification of novel biologically active molecules, including drug repurposing. Whether for ligand-based or for structure-based virtual screening, a chemical collection needs to be properly processed prior
Comparison of 71 bipolar disorder pharmacotherapies for kidney disorder risk: The potential hazards of polypharmacy
Read Article Newly observed KD occurred in 14,713 patients. No regimen had significantly lower risk of KDs than “No drug”. The HR estimates ranged 0.86–2.66 for “all” KDs and 0.87–5.30 for “severe” KDs. As additional drugs were combined to compare
Here you can search Publications by Author. Tudor Oprea, M.D., Ph.D. PubMed Google Scholar Cristian Bologa Ph.D. PubMed Google Scholar Browse Our Latest Publications.
Bioinformatics and Drug Discovery 3rd Edition, Editors: Dr. Larson & Dr. OpreaCover Design: Jayme Holmes Buy on Amazon Dr. Kroth’s Book Available! Health Care USA, Ninth Edition. Dr. Lambert’s book available, “Human Genome Informatics”. Human Genome Informatics: Translating Genes into
UNM Scientists Studying Ways to Repurpose Older Drugs to Treat COVID-19 Infection. Read more
Listen to the podcast:http://www.drgpcr.com/episode-18-a.i.-and-gpcr-with-dr.-yamina-berchiche/
The goal of the Illuminating the Druggable Genome (IDG) program is to improve our understanding of the properties and functions of proteins that are currently unannotated within the three most commonly drug-targeted protein families: G-protein coupled receptors, ion channels, and
DrugCentral is online drug information resource created and maintained by Division of Translational Informatics at University of New Mexico. DrugCentral provides information on active ingredients chemical entities, pharmaceutical products, drug mode of action, indications, pharmacologic action. We monitor FDA, EMA,
Drug Repurposing Projects Ketorolac Virtual screening by TiD identified the R-enantiomer of ketorolac as a hit for blocking GTPase activation in response to growth factor stimulus. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief under the trade
FACILITIES AND OTHER RESOURCES UNIVERSITY OF NEW MEXICO Translational Informatics Division The Translational Informatics Division (TID) is housed in the Innovation Discovery & Training Complex (IDTC) together with the UNM Center for Molecular Discovery (UNMCMD). TID is part of the
Cheminformatics is the application of informatics and computation to chemistry. Historically, cheminformatics has been associated with drug discovery science. Cheminformatics encompasses a wide range of foundational disciplines and computational technologies, from graph theory based molecular representations, to machine learning based
Translational Bioinformatics (TBI): The science of leveraging biomolecular data into clinical medicine. Here is a much longer definition from the American Medical Informatics Association site. Translational Bioinformatics is the development of storage, analytic, and interpretive methods to optimize the transformation
Fellowship NOW Being Offered at UNM The Department of Internal Medicine is starting a new Clinical Informatics Fellowship. For more information, click HERE Clinical Informatics is the application of health information technologies to help in the quality of health care,
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The goal of the Illuminating the Druggable Genome (IDG) program is to improve our understanding of the properties and functions of proteins that are currently unannotated within the three most commonly drug-targeted protein families: G-protein coupled receptors, ion channels, andRead more
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