Translational Informatics Talks and Conferences
TiD has a long tradition of collaboration with leading clinicians and scientists. In working with these leaders, we have sponsored numerous speaker series from “Drug Discovery Days” to “Grand Rounds.” Below is a list of innovative speakers TiD has sponsored throughout the past decade along with many cutting-edge presentation materials and recordings.
2018
Tudor Oprea,UNM Translational Informatics: SAHLGRENSKA ACADEMY SEMINARS: March 5th 2018
2017
Tudor Oprea, UNM,Translational Informatics: Zika Virus Symposium – Watch/Listen
TiD DoIM Grand Rounds:
Jeff Blaney, Genentech, Enabling the Best Structure-Based Design Engine: A Human Expert
Soren Brunak, DTU, Fine-Grained Phenotypes, Comorbidities and Disease Trajectories from Data Mining of Electronic Patient Records
Tudor Oprea, UNM, UNM Translational Informatics: A Brief Overview
William Hersh, OHSU, Clinical Informatics Subspecialty: What It Is and Why It’s Important
Mark Unruh, UNM, Hemodialysis Frequency Trials: Can Modeling Help Us Tailor Treatment?
Joshua Swamidass, WUSTL, Gaining Clinical Insight from Chemical Data
Leslie Benet, UCSF, Clearance Isn’t Only a Big Sale and Transporters Are Not Limited to Trucks
Subramani Mani & Herbert Davis, UNM, Predictive Modeling Using Machine Learning for Clinical Decision Making & I2B2 and ACG
Check out the TiD Internal Medicine Workshop HERE !!!
Conference Archives:
See below for archives of past conferences
Drug Discovery Day
From Molecules to Translational Research
Organized by the UNM Center for Molecular Discovery, the UNM Cancer Center, and the Division of Biocomputing
Monday, April 30, 2012
- Morning session: Domenici Center for Health Sciences Education, 8:30am-11:20 a.m.
- Lunch: Cancer Center Foyer, 11:30 a.m.
- Afternoon session: UNM Cancer Center Auditorium, noon -4:30 p.m.
Speakers
- Richard Larson, MD/PhD (UNM), Drug Discovery and Development: NIH and the UNM Health Science Center
- Karlett Parra, PhD (UNM), Vacuolar ATPase: a Model Proton Pump for Antifungal Drug Discovery
- Pope Moseley, MD (UNM), Translational Medicine
- Tudor Oprea, MD/PhD (UNM), Translational Informatics
- Gergely Zahoranszky-Kohalmi (UNM), CARLSBAD: Chemical patterns, biological networks
- Stephen Baylin, MD (Johns Hopkins), Featured lecture: The Cancer Epigenome – Origins and Translational Implications
- Larry Sklar, PhD (UNM), Drug Discovery Opportunities at UNMCMD
- Ruben Abagyan, PhD (UCSD), Featured lecture: Predicting Activity of Compounds by Docking to the Pocketome
- Cheryl Willman, MD (UNM),Translational Research at the UNM Cancer Center
- Angela Wandinger-Ness, PhD (UNM), GTPases and Ovarian Cancer
- Eric Prossnitz, PhD (UNM), What have novel GPER-selective ligands told us about mechanisms of estrogen action?
Drug Discovery Day
A One Day Conference on Biomolecular Discovery, Discovery Informatics and Computation
Sponsored by Division of Biocomputing, the UNM Center for Molecular Discovery, the UNM Cancer Center and Novartis Institutes for Biomedical Research
Friday, April 29, 2011
Domenici Center for Health Sciences Education
Keynote address
Klaus-Robert Muller, (Technische Universität Berlin)
Predicting Properties of Small Molecules with Kernel-Based Machine Learning Methods
Speakers
- Jeremy Edwards (UNM & NMSTMC), Spatial modeling of the ErbB signaling network
- Christopher Bayly (OpenEye Scientific Software), Pursuing entropy and structured water for lead optimization: why bother?
- Vageli Coutsias (UNM), Protein Loop Modeling with Inverse Kinematics
- Donovan Chin (Novartis Institutes for Biomedical Research), Identifying non-basic amine building blocks with good solubilizing power that do not introduce hERG using computational informatics techniques
- Fabio Broccatelli (Università di Perugia & UCSF), The Use of BDDCS in Early Drug Discovery
- Angela Wandinger-Ness (UNM), Rac1 and Cdc42 GTPases as Novel Targets in Ovarian Cancer
- Tudor Oprea (UNM & Danmarks Tekniske Universitet), Computer-Aided Drug Repurposing: Some Fact, Some Fantasy
- Jeff Arterburn (NMSU & NM-INBRE), Design and synthesis of tritylthioethanamine probes with potent KSP inhibitory activity
- Susan R. Atlas (UNM & CARC), Three Problems in Computational Cancer Biology
Drug Discovery Day
A one-day conference on biocomputing
Organized by the UNM Center for Molecular Discovery and the Division of Biocomputing
Friday, April 16, 2010
Domenici Center for Health Sciences Education
Keynote address
Chris Lipinski (Pfizer, retired)
Drug repurposing: strengths, weaknesses and application to rare and orphan diseases
Speakers
- Robert Hromas (UNM), Targeting Transposase Domain Proteins to Enhance Cancer Therapy
- Bridget Wilson (UNM), Computational Challenges at the NM Center for Spatiotemporal Modeling Center (an NIGMS-funded National Center for Systems Biology)
- Graham Timmins (UNM), Stable Isotope Enhanced Antibiotics
- Todd Thompson (UNM), From Antihistamine to Promising Prostate Cancer Treatment: Repurposing Astemizole
- Hattie Gresham (UNM), Repurposing an existing gout drug complexed with cyclodextrin to target Staphylococcus aureus virulence
- Tudor Oprea (UNM), Drug Repurposing at UNM
- Larry Sklar, Mark Burge and Cristian Bologa (UNM), UNM and Drug Repositioning
- Steven Seifert (UNM), Cyclobenzaprine and the Serotonin Syndrome
UNM Student Award for Innovation in Informatics
The UNM Student Award for Innovation in Informatics is awarded to a UNM graduate or undergraduate student for the best paper describing innovation or research in the field of informatics.
2010 winner
Soumya Banerjee (UNM)
A Mathematical Model of Body Size Effects on Pathogen Replication and Immune Response Rates
Biocomputing @ UNM
Discovery Informatics: From Biology to Chemistry and Medicine
A one-day conference on biocomputing: Friday, March 27, 2009
Organized by the UNM Center for Molecular Discovery and the Division of Biocomputing
Location: Domenici Center for Health Sciences Education
Keynote address
Dimitris Agrafiotis (Johnson & Johnson)
Discovery informatics on an industrial scale – The past, present and future of ABCD
Speakers
- Robert Hromas (UNM), Targeting DNA Repair Components to Improve Cancer Chemotherapy
- Pamela Hall (UNM), Small molecule inhibitors of hantavirus infection
- Eric Prossnitz (UNM), What has a selective GPR30 estrogen receptor agonist revealed in three years?
- Todd Thompson (UNM), Identification of Small Molecule Probes That Induce Granularity and Cell Death in Prostate Cancer Cells Using the Hyper-Cyt High-Throughput Flow Cytometry System – Screening for Novel Prostate Cancer Therapeutic Agents
- Colleen Jonsson (Southern Research Institute), High throughput screening of BSL3 pathogens; lessons learned on the path to chemical probe discovery
- Bruce Edwards (UNM), Flow Cytometry Sushi: Preparing and Serving Raw Data for Public Consumption
- Omdahl Lecture: Andy Annalora (Scripps), The Crystal Structure of Cytochrome P450C24A1 (CYP24A1) of the Vitamin D Pathway
- Stephen Boyer (IBM), Text Analytics Applied to Healthcare & Life Science
- Stephen Faraci (Pfizer), Pfizer’s Biotherapeutic and Bioinnovation Center: a unique approach in discovering novel biotherapeutic drugs
- John Lowe (Pfizer, retired), Characterization of the NK1 (Substance P) Receptor Using Nonpeptide NK1 Receptor Antagonists
Biocomputing @UNM
HTS Informatics and Cheminformatics: How do we extract the most of the data
A one-day conference on biocomputing: Friday, March 28, 2008
Organized by the Division of Biocomputing and the UNM Cancer Center
Location: Domenici Center for Health Sciences Education
Keynote address
Nikolay Savchuk (ChemDiv)
Academic institutions play most important part in basic research and that includes life sciences
Speakers
- Ajit Jadhav (NIH/NCGC), An open source cheminformatics system for HTS data analysis
- James P. Snyder (Emory/SOM), Foiling Nasty Viruses: Paramyxovirus Containment
- Judith V. Hobrath (Southern Research), Cheminformatics for the Probe Development Process using Commercially Available Tools
- Stephan Schürer (Scripps Florida), Informatics integration to facilitate lead discovery and optimization
- Ying Su (Burnham), Compound Registration System: persistent challenges or new challenges?
- Laurel Sillerud (UNM/BMB), NMR and Biocomputing in Drug Design
- Cristian Bologa (UNM/Biocomputing), Scaffold-based analysis of bioactivity databases
- Elebeoba E. May (Sandia), Quantitative Studies of Latency/Reactivation in a Murine Model of Mycobacterium tuberculosis Infection
- Stefan Furrer (Givaudan), New Developments in the Chemistry of Cooling Compounds
- John J. Irwin (UCSF), Quantitatively relating proteins by their ligands
- Eric Prossnitz (UNM/CRTC), The Search for Novel Estrogen Receptor Modulators
- Bruce Edwards (UNM/CRTC), High throughput flow cytometry to detect selective inhibtors of ABCB1, ABCC1 and ABCG2 transporters
- Larry A. Sklar (UNM/CRTC), HTS Flow Cytometry of Multiplexed Targets
- Todd Thompson (UNM/COP) Assays for prostate cancer therapeutic agents, small molecule library screening, and bioinformatic data interpretation: the biologist, chemist, bioinformaticist waltz
UNM Student Award for Innovation in Informatics
The UNM Student Award for Innovation in Informatics is awarded to a UNM graduate or undergraduate student for the best paper describing innovation or research in the field of informatics.
2008 winner
Nate Swanson (UNM/CS)
Dynamic Dose Delivery Model for Gamma Knife Radiosurgery
Biocomputing @ UNM
HTS Informatics and Cheminformatics: How do we extract the most of the data
A one-day conference on biocomputing: Friday, March 30, 2007
Sponsored by the Division of Biocomputing, the New Mexico Molecular Libraries Screening Center (NMMLSC), and the UNM Cancer Center.
Location: Domenici Center for Health Sciences Education
Keynote address
Leslie Z. Benet (UCSF)
Biopharmaceutics Drug Disposition Classification System and Its Use in Deriving QSAR Approaches
Speakers
- Scott Burchiel (UNM/COP): Toxciogenomic Approaches to Understanding Benzo(a)pyrene-Quinone Signaling in Human Mammary Epithelial Cells
- Alex Kiselyov (ChemDiv): Biology-Driven Chemical Diversity: A Novel Approach in Identification of Specific and Dual Inhibitors of PI3 Kinases
- Alexander Tropsha (UNC): Screening Data
- Chris Waller (Pfizer): Strategies for Data and Systems Integration in Support of Drug Discovery
- Eric Prossnitz (UNM/CRTC): Targeting Classical Estrogen Receptors and GPR30
- Jeffrey B. Arterburn (NMSU): Design and Synthesis of Cyclopenta[c]quinoline Derivatives as Selective Ligands for GPR30
- Eugen Brailoiu (Temple): Estrogen Receptor GPR30 and Endothelial Cells
- Nae Dun (Temple): Distribution of GPR30 Immunoreactivity in the Rat Brain, Spinal Cord and Peripheral Tissues
- John MacCuish (Mesa): Where Bioinformatics and Cheminformatics Meet: A Virtual Classroom
- Mike Brown (Sandia): Efficient Calculation of Molecular Properties from Simulation using Kernel Molecular Dynamics
- Jean-Loup Faulon (Sandia): Genome Scale Enzyme-Metabolite and Drug-Target Interaction Predictions using Support Vector Machine
- Bruce Edwards (UNM/CRTC): Multiplexing of Cell-Based Bioassays to Maximize Biological Content and Efficiency in High Throughput Screening
- Larry Sklar (UNM/CRTC): High Throughput Flow Cytometry of Multiplexed Targets for Partnerships in Discovery
- Todd Thompson (UNM/COP): High-throughput Screening of Androgen Receptor Activity Modulators
UNM Student Award for Innovation in Informatics
The UNM Student Award for Innovation in Informatics is awarded to a UNM graduate or undergraduate student for the best paper describing innovation or research in the field of informatics.
2007 winner
Kristina J. Anderson (UNM/Biology)
Temporal Patterns in Rates of Community Change during Succession
Biocomputing @UNM
A one-day workshop on biocomputing: Monday, April 17, 2006
Sponsored by the Division of Biocomputing, the New Mexico Molecular Libraries Screening Center (NMMLSC), and the New Mexico Center for Environmental Health Sciences (NIEHS).
Location: Health Sciences and Services Building 105
Lunch: Research Incubator Building commons
Keynote address
Christopher A. Lipinski (Pfizer)
Target Validation, Drug Discovery, Chemistry Space and Biology-Chemistry Disconnects
Speakers
- Scott W. Burchiel (New Mexico NIEHS Center): Analysis of Genomic Effects of Benzo(a)Pyrene-Quinones (BPQs) in Human Mammary Epithelial Cells
- Stanly Steinberg (Mathematics and Statistics): The Motion of Macromolecules on the Cell Membrane
- James R. Faeder (LANL): Rule-based Modeling of Biochemical Networks
- Chang-Shung Tung (LANL): Structural Modeling of Biomolecular Complexes
- Sara Pollock (Biocomputing): Systematic Enumeration of Molecular Scaffolds
- John MacCuish (Mesa Analytics & Computing): Cheminformatics Virtual Classroom
- Tudor Oprea (Biocomputing): How does Cheminformatics Contribute to Lead and Drug Discovery
- Hua Guo (Chemistry): Quantum Mechanical/Molecular Mechanical Studies of Beta-lactamase Catalysis
- Danny Rintoul (Sandia): Information Content in Typical Biological Data
- James P. Snyder (Emory University): High-, Low- and No-Throughput Screening: Getting Off the Ground in a University Molecular Design Environment
- Maurizio Pellecchia (Burnham Institute): A Million Little Pieces: Fragment Based Approaches to Drug Discovery
- Bruce Edwards (Cytometry): Integration of Virtual Screening With High Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor Antagonists
- Eric Prossnitz (Cell Biology and Physiology): Virtual and Biomolecular Screening Identify Novel Estrogen Receptor Ligands
- Herbert Tanner (Mechanical Engineering): The Use of Formal Methods for the Analysis of Bottlenecks in High Throughput Screening
- Larry A. Sklar (Pathology): New Mexico Molecular Libraries Screening Center
UNM Student Award for Innovation in Informatics
The UNM Student Award for Innovation in Informatics is awarded to a UNM graduate or undergraduate student for the best paper describing innovation or research in the field of informatics.
2006 winner
Nicholas D. Pattengale (Computer Science)
A Sublinear-Time Randomized Approximation Scheme for the Robinson-Foulds Metric
Biocomputing @ UNM
A one-day workshop on biocomputing: Friday, April 22, 2005
The Office of Biocomputing is running a one day workshop on local uses of biocomputing (a broad category covering biology, medical research and bioX [where X = chemistry, engineering, physics, statistics, etc.] significantly aided by computers) The idea here is to nurture interaction and recognition within the UNM and local community of those people interested in various aspects of biocomputing.
Sponsored by the Division of Biocomputing and the New Mexico Center for Environmental Health Sciences (NIEHS).
Location: Basic Medical Sciences Building 303
Lunch: Research Incubator Building commons
Keynote address
I. D. (Tack) Kuntz (University of California, San Francisco)
Computer-Assisted Ligand Design
Speakers
- Stephen L. Mathias (Office of Biocomputing): Pathway Databases and Resources
- Bill Beavis (National Center for Genome Resources): At the Interface of Quantitative Genetics and Systems Biology
- Jack K. Horner (Science Applications International Corporation): An Automatic Relevance Determination Method for Identifying the Signature of Stage I Ovarian Cancer in the Mass-Spectrum of Serum Proteins
- Jeremy S. Edwards (University of Delaware): Computational Modeling Reveals Molecular Details of Epidermal Growth Factor Binding
- Philip J. Kroth (Health Sciences Library and Informatics Center): UNM Virtual Human Biospecimen Repository: Pitfalls and the Possibilities
- Christian Forst (Los Alamos National Laboratory): Biological Network Analysis by a Network Proteomics Approach and Subcellular Protein Profiling
- Sorin G. Popa (Feldmatech): Novel Biocomputing Approach for Lung Cancer Detection and Imaging
- Mary Z. Fuka (Wild Rose Biophysics): An Overview of Grid Computing in the Life Sciences
- Eric R. Prossnitz (Cell Biology and Physiology): Isolation for Compounds Specific to Classical and Novel Steroid Receptors
- Tudor I. Oprea (Office of Biocomputing): Virtual Screening at UNM: an Overview
- Jean-Loup Faulon (Sandia-Livermore National Laboratories): Biological and Chemical Structures Inference and Design
- Michael A. Kappler (Daylight Chemical Information Systems): GENSMI: Exhaustive Enumeration of Simple Graphs
- Norah MacCuish (Mesa Analytics & Computing): Cheminformatics Virtual Classroom
- Kevin Cahill (Physics and Astronomy): The Hybrid Potential
UNM Student Award for Innovation in Informatics
The UNM Student Award for Innovation in Informatics is awarded to a UNM graduate or undergraduate student for the best paper describing innovation or research in the field of informatics.
2005 winner
Sushmita Roy (Department of Computer Science)
Cell Population Deconvolution from Microarray Data using Particle Filters
Biocomputing @UNM
A one-day workshop on biocomputing: Monday, April 12, 2004
The Office of Biocomputing is running a one day workshop on local uses of biocomputing (a broad category covering biology, medical research and bioX [where X = chemistry, engineering, physics, statistics, etc.] significantly aided by computers) The idea here is to nurture interaction and recognition within the UNM and local community of those people interested in various aspects of biocomputing.
Sponsored by the Division of Biocomputing and the New Mexico Center for Environmental Health Sciences (NIEHS).
Location: The Santa Ana Room (upper level, east side) in the Student Union Building, University of New Mexico main campus
Speakers
- Bernard Moret (Computer Science, UNM): CIPRES: A National Resource in Phyloinformatics and Computational Phylogenetics to Support the Reconstruction of the Tree of Life
- Danny Rintoul (Sandia National Laboratories): Sandia’s Genomes to Life Project, an Overview
- Gavin Pickett (KUGR Facility, Cancer Center, UNM): Data Mining in the Land of Genomics
- Steve Mathias (Biocomputing, UNM): Genomics Database Applications at UNM
- James Degnan (Mathematics and Statistics, UNM): Maximum Likelihood Inference of Species Trees Under the Coalescent Process
- Ed Bedrick (Mathematics and Statistics, UNM): Predicting the Probability of Abortion in Dairy Cows: A Hierarchical Bayesian Logistic-Survival Model using Sequential Pregnancy Data
- Christy Warrender (Computer Science, UNM): Modeling Intercellular Interactions in the Peripheral Immune System
- John K. Prentice (Quetzal Biomedical, Inc. and Wild Rose Biophysics): The Use of Whole Heart Computer Modeling in the Development of Advanced Electrophysiological Treatments for Congestive Heart Failure
- Laurel Sillerud (Biochemistry and Molecular Biology, UNM): Computer-Aided Solution of the Inverse Field Problem for High-Sensitivity Biomagnetometry
- Fred Hashimoto (Internal Medicine, UNM): The Electronic Medical Record
- Phil Kroth (Health Sciences Library and Informatics Center, UNM): Medical Informatics at the UNM Health Sciences Center – Taking Science Where it has Never Gone Before
- Avinash Kewalramani (LANL): BioFilter: An Architecture for Parallel Deployment and Dynamic Chaining of Standalone Bioinformatics Tools
- Larry Sklar (Pathology, UNM): Analysis and Modeling of Signal Transduction Molecular Assemblies
- Bruce Edwards (Flow Cytometry, Pathology, UNM): High Throughput Flow Cytometry to Identify Small-Molecule Formyl-Peptide Receptor (FPR) Ligands
- Tudor Oprea (Biocomputing, UNM): Ligand-Based Virtual Screening for Small-Molecule Formyl-Peptide Receptor (FPR) Ligands
- Vageli Coutsias (Mathematics and Statistics, UNM): Geometrical RING Optimization: An Efficient Method for Structure Determination of Ring Molecules
- Hua Guo (Chemistry, UNM): Quantum Mechanical/Molecular Mechanical (QM/MM) Approaches to Reactions Catalyzed by Enzymes
Posters
- Tharun Kumar Allu and Tudor I. Oprea (Department of Computer Science and Office of Biocomputing, University of New Mexico School of Medicine): Steroid Metabolic Pathways: An Analysis of Water Solubility
- Anna Waller (Cytometry Department, Health Sciences Center, University of New Mexico): Ternary Complex Model for Detergen Solubilized G-Protein Coupled Receptors
Biocomputing @UNM
A one-day workshop on biocomputing: Thursday, April 3, 2003
The Office of Biocomputing is running a one day workshop on local uses of biocomputing (a broad category covering biology/biochemistry/medical research significantly aided by computers, which includes biostatistics). The idea here is to nurture interaction and recognition within the UNM community of those people interested in various aspects of biocomputing.
Sponsored by the Division of Biocomputing and the New Mexico Center for Environmental Health Sciences (NIEHS).
Location: 8:30 am-12 noon: Nursing/Pharmacy 257
Noon-5:00 pm: Health Sciences Services Building (HSSB) 105
Speakers
- Scott Ness (Molecular Genetics and Microbiology): Gene Expression Data – Biocomputing Successes and Challenges
- Susan Atlas (Physics and Astronomy): Computational Biology and Genomics for Cancer Drug Discovery
- Stephanie Ruby (Molecular Genetics and Microbiology): Genetic Regulatory Networks and Visualization Tools
- Fred Hashimoto (Internal Medicine): The Electronic Medical Record
- Holly Buchanan (HSC Library): Role of the Health Sciences Library and Informatics Center
- Marc Ingber (HPC@UNM): An Overview of the Biocomputing Research Thrust at HPC@UNM
- Chris Stidley (Family and Community Medicine): Overview of Biostatistics at UNMHSC
- Bernard Moret (Computer Science): Phylogeny Reconstruction from Whole-Genome Data: A Computational Perspective
- Guy Brock (Mathematics and Statistics): Inference of Regulatory Networks From Microarray Data
- Stanly Steinberg (Mathematics and Statistics): Topographical Analysis of the IgE Receptor Signaling Pathway of Mast Cells
- Bridget Wilson (Pathology): Reaction Diffusion Modeling of ER Calcium Levels with Realistic Geometry: Effects of IP3 Receptor Clustering
- John Engen (Chemistry): Biocomputing in Bioanalytical Mass Spectrometry and Proteomics
- Steve Jett (Cell Biology and Physiology): Crystallography without Crystals: SPIDER and Single Particle Reconstruction
- Tudor Oprea (Biocomputing): Cheminformatics: A Brief Overview
- Bryan Shiloff and Andy Pineda (Biocomputing and HPC@UNM): Virtual Screening of a Large Chemical Library on a Linux Cluster
- Vageli Coutsias (Mathematics and Statistics): Exact Analytical Formulation for Coordinated Motion in Polypeptide Chains
- Mike Brown (Biochemistry and Molecular Biology): New Approach for Characterization of Binding-Site Search Space