Linking diseases, drugs and the druggable proteome.
The Illuminating the Druggable Genome Knowledge Management Center (IDG KMC) evaluates, organizes and distils more than 80 protein-centric and over 20 gene-centric resources for over 20,000 curated human proteins (UniProt). The IDG KMC currently focuses on four protein families: G-Protein Coupled Receptors, Nuclear Receptors, Ion Channels and Kinases. However, data integration concerns all human proteins curated in UniProt.
Discovery of Inhibitor of Fructose Transporter Offers Novel Treatment for Diabetes and Cancer
Tudor I. Oprea, M.D., Ph.D. Cristian-George Bologa, Ph.D. Oleg Ursu, Ph.D.
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