Section II

The Structure of Macromolecules: Assignments

Assignment 1:

• go to Entrez NCBI website
• search for color blindness
• get opsin 1 (cone pigments), long-wave-sensitive (Homo sapiens) that encodes for a red light absorbing visual pigment of the opsin gene family
• search PDB
• retrieve 1F88 and generate opsin model
• how is color blindness (what chromosomes) linked to GPCRs?